Abstract
The Hodgkin lymphoma (HL) showed a good prognosis in Erbil city. However, a number of deaths were reported. The monitoring and treatment strategies for HL had improved in the last decade. To evaluate the prognostic value of interim PET/CT scan in HL patients and predict the survival outcome in addition to its effect on progression-free survival of HL patients. A retrospective cross-sectional study was conducted in Nanakali hospital in Erbil city in the Kurdistan region of Iraq through reviewing data of patients with Hodgkin lymphoma from the 1st of January, 2014 to the 31st of December, 2019 on a sample of seventy-five Hodgkin lymphoma patients. The diagnosis of Hodgkin lymphoma by a physician was done in regard to lymph biopsy by World Health Organization criteria. The PET/CT scan was done after two treatment cycles. PET/CT of HL patients was done in a private center in Erbil city (Media Diagnostic Center). The mean overall survival duration of HL patients was 5.39 years with an overall survival rate of 92% and the mean progression-free survival duration of HL patients was 5.04 years with a progression-free survival rate of 76%. The mean overall survival of HL patients with positive interim PET/CT was (4 years and a rate of 75%) which was lower than the mean overall survival of HL patients with negative interim PET/CT (7.2 years and a rate of 95.2%), with a significant difference (p<0.001). The interim PET/CT scan is useful in the prognosis of patients with Hodgkin lymphoma and in predicting overall survival and mortality.
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