Abstract

Postinflammatory hyperpigmentation is a reactive hypermelanosis that develops following cutaneous inflammation. Common causes of this condition include intrinsic skin conditions as well as external insults to the skin, including infections. Human immunodeficiency virus (HIV)-associated oral melanotic hyperpigmentation is categorized under "lesions less commonly associated with HIV infection." The aim of this study is to report a case of an HIV-associated oral mucosal melanin hyperpigmentation. A 55-year-old man attended the referral service in oral diagnosis, presenting a blackened spot, showing smooth surface and irregular borders in the region of the right jugal mucosa, measuring about 2 cm in diameter. The patient had previous diagnosis of HIV and did not show pigmentation in other regions of the body. An incisional biopsy was performed. The histopathological examination showed pigmentary incontinence of melanophages in the subepithelial region. The patient is under medical supervision and using antiretrovirals. In addition, he will be observed to follow the evolution of oral condition. Postinflammatory hyperpigmentation is a reactive hypermelanosis that develops following cutaneous inflammation. Common causes of this condition include intrinsic skin conditions as well as external insults to the skin, including infections. Human immunodeficiency virus (HIV)-associated oral melanotic hyperpigmentation is categorized under "lesions less commonly associated with HIV infection." The aim of this study is to report a case of an HIV-associated oral mucosal melanin hyperpigmentation. A 55-year-old man attended the referral service in oral diagnosis, presenting a blackened spot, showing smooth surface and irregular borders in the region of the right jugal mucosa, measuring about 2 cm in diameter. The patient had previous diagnosis of HIV and did not show pigmentation in other regions of the body. An incisional biopsy was performed. The histopathological examination showed pigmentary incontinence of melanophages in the subepithelial region. The patient is under medical supervision and using antiretrovirals. In addition, he will be observed to follow the evolution of oral condition.

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