Abstract

There is a dearth of evidence on injection drug use and associated HIV infections in Kenya. To generate population-based estimates of characteristics and HIV/STI prevalence among people who inject drugs (PWID) in Nairobi, a cross-sectional study was conducted with 269 PWID using respondent-driven sampling. PWID were predominantly male (92.5 %). An estimated 67.3 % engaged in at least one risky injection practice in a typical month. HIV prevalence was 18.7 % (95 % CI 12.3–26.7), while STI prevalence was lower [syphilis: 1.7 % (95 % CI 0.2–6.0); gonorrhea: 1.5 % (95 % CI 0.1–4.9); and Chlamydia: 4.2 % (95 % CI 1.2–7.8)]. HIV infection was associated with being female (aOR, 3.5; p = 0.048), having first injected drugs 5 or more years ago (aOR, 4.3; p = 0.002), and ever having practiced receptive syringe sharing (aOR, 6.2; p = 0.001). Comprehensive harm reduction programs tailored toward PWID and their sex partners must be fully implemented as part of Kenya’s national HIV prevention strategy.

Highlights

  • Injection drug behaviors have been recognized as key facilitators of HIV transmission since the beginning of the epidemic [1,2,3]

  • Comprehensive harm reduction programs tailored toward people who inject drugs (PWID) and their sex partners must be fully implemented as part of Kenya’s national HIV prevention strategy

  • While Southeast and East Asia have the largest number of PWID [4], recent evidence shows an increase in injection drug use and associated HIV infections in sub-Saharan Africa, where the burden of HIV is already the highest in the world [5,6,7,8,9,10,11,12,13,14,15,16]

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Summary

Introduction

Injection drug behaviors have been recognized as key facilitators of HIV transmission since the beginning of the epidemic [1,2,3]. While Southeast and East Asia have the largest number of PWID [4], recent evidence shows an increase in injection drug use and associated HIV infections in sub-Saharan Africa, where the burden of HIV is already the highest in the world [5,6,7,8,9,10,11,12,13,14,15,16]. Despite a lack of comprehensive evidence, it is clear that PWID in subSaharan Africa are at great risk for acquiring and. M. Sheehy Population Council, New York, NY, USA. D. Broz HHS-Centers for Disease Control and Prevention, Division of Global HIV/AIDS, Center for Global Health, Atlanta, GA, USA

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