Abstract
Promising evidence on the validity ofwhat came to be called 'psychoimmunology' (PI) has been recorded since the time of Galen, who reputedly observed that women of a melancholic temperament were more prone to develop cancer than those of a sanguine nature2. Forthcoming evidence, on the other hand, has fallen far short of the ideal. Conclusive evidence of clear links between disease, immunity and psychological factors is very rare. Despite this, new findings are looked upon with an interest and enthusiasm that even the most circumspect of observers finds hard to disguise. A relatively recent editorial in The Lancet3, which reviewed evidence for, and questioned the clinical importance of, a link between emotion and immunity, concluded:
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