Abstract

Autologous skin grafting was developed more than 3500 years ago. Several approaches and techniques have been discovered and established in burn care since then. Great achievements were made during the 19th and 20th century. Many of these techniques are still part of the surgical burn care. Today, autologous skin grafting is still considered to be the gold standard for burn wound coverage. The present paper gives an overview about the evolution of skin grafting and its usage in burn care nowadays.

Highlights

  • The skin is the largest organ of the human body and the first line of defense against harmful influences such as mechanical forces, microorganisms, or radiation.It maintains thermoregulation and fluid balance as well as acts as a sensory organ that is able to register pressure, temperature, and pain, due to specific receptors

  • While the usage of meshed split thickness skin grafting is the best option for the treatment of extensive burns, unmeshed sheet grafting is used for small burns and in aesthetically important regions

  • Sheet grafts are commonly used for small burns,burns, while which is caused by a lack of donor sites

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Summary

Introduction

The skin is the largest organ of the human body and the first line of defense against harmful influences such as mechanical forces, microorganisms, or radiation. It maintains thermoregulation and fluid balance as well as acts as a sensory organ that is able to register pressure, temperature, and pain, due to specific receptors. Full-thickness skin grafting achieves the best aesthetic and functional results in burn injury reconstruction [3,4,5]. This article gives an overview about the historical evolution of skin grafting, including the development of common techniques, and further explains their usage in burn care nowadays. The split-thickness skin graft associated donor site problems are analyzed, and solutions are discussed

The Origin of Skin Grafting
The Split-Thickness Skin Graft
Mesh Graft
Meek Technique
The Full-Thickness Skin Graft
Allogeneic and Xenogeneic Transplants
A Brief History of Skin Substitutes and Their Use Today
Cell Cultures
Dermal Substitutes
Cell Suspension
The Curse of Donor Site Morbidity
The Dermis Graft—A Novel Approach
Conclusions
Findings
Limitations
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