Abstract
One of the most significant contributions to medicine—William Harvey's concept of the circulation of the blood—was quietly announced early in the 17th century with the publication of a book, De Motu Cordis. This book, a culmination of thought, observation and controlled testing with conclusions based on the results of repeated experiments, changed the course of medical thinking. The year just ended, 1978, presented at least two excellent reasons to commemorate and to honor William Harvey. First, Harvey was born on April 1, 1578, and we celebrated the 400th anniversary of his birth; second, 1978 also marked the 350th anniversary of the publication date of his epoch-making classic, De Motu Cordis.
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