Abstract
Histoplasmosis is an infection usually caused by a fungal pathogen that, in most cases, occurs in the respiratory tract, which explains the high frequency of clinical manifestations in the lungs. (1) This mycosis is endemic in the Americas (Mississippi and Ohio River Valley, USA; Central and South America; and the West Indies), while reports in areas of Asia, Africa, Australia, and Oceania are mainly associated with the pandemic of acquired immune deficiency syndrome (AIDS). In Europe, cases are on the rise because of the speculation of a global distribution of histoplasmosis, and emphasis has been on improving methods for its diagnosis. (2,3)
Highlights
Histoplasmosis mostly affects the lungs; caused by a fungal pathogen that, in most cases, the clinical presentation depends on occurs in the respiratory tract, which explains two variables: the load of infectious particles the high frequency of clinical manifestations in in the inoculum and the immune status of the the lungs
Are on the rise because of the speculation of mm3), or in therapy with tumor necrosis factor a global distribution of histoplasmosis, and inhibiting agents, in which mortality rates are emphasis has been on improving methods high if diagnosis and treatment are not timely
The etiological agent of histoplasmosis is sis are nonspecific, so its differentiation with the dimorphic fungus Histoplasma capsula- other infections, especially tuberculosis, is a tum, which is widely distributed in soils with challenge, even to determine the presence of high nitrogen content both in endemic with HIV/AIDS. [1,2,4]
Summary
Histoplasmosis mostly affects the lungs; caused by a fungal pathogen that, in most cases, the clinical presentation depends on occurs in the respiratory tract, which explains two variables: the load of infectious particles the high frequency of clinical manifestations in in the inoculum and the immune status of the the lungs. [1] This mycosis is endemic in the patient. The etiological agent of histoplasmosis is sis are nonspecific, so its differentiation with the dimorphic fungus Histoplasma capsula- other infections, especially tuberculosis, is a tum, which is widely distributed in soils with challenge, even to determine the presence of high nitrogen content (contaminated with coinfections that occur frequently in patients droppings from bats or birds) both in endemic with HIV/AIDS.
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