Abstract
Aeromonas caviae is one of the predominant motile aeromonads in Nile tilapia, Oreochromis niloticus . In this study, the histopathological alterations in the kidney, liver and pancreas of O. niloticus juveniles experimentally challenged with α-haemolytic A. caviae is described. The Nile tilapia experienced 60% mortalities at a challenge dose of 6×10 8 cells/fish. Post-challenge, well-defined histopathological changes were observed with nephritis and the loss of structural integrity of the kidney tissues. The liver was dispersed, necrotized and had fatty changes in the hepatic parenchyma. Inflammation of the pancreas, as well as pancreatic acinar cells and disintegration of intrahepatic exocrine pancreatic tissues, were also noted. The results, thus, demonstrated that A. caviae can cause severe damages in the kidney, liver and pancreas of O. niloticus , similar to those of other known fish bacterial pathogens.
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