Abstract
Histological changes of vaginal and ectocervical mucosa in women of reproductive age suffering from vaginal candidosis are described. The epithelial surface is covered with adherent masses composed of desquamated and destroyed epithelial cells and leucocytes impregnated with proteinaceous fluid and penetrated by pseudomycelium. The outer epithelial layers are characterized by dystrophic and necrobiotic changes, desquamation, formation of fissures and small cavities. Pseudomycelium penetrates 4 to 6 superficial epithelial layers. The barrier between the invading pseudomycelium and the blood vessels of the lamina propria papillae in some sites is only 5 to 6 flattened epithelial cells thick. In the basal epithelial layer, increased mitotic activity is noted. Lamina propria contains lympho-plasmocytic infiltrates. The problems of pathogenesis and diagnosis of vaginal candidosis are discussed in connection with the present findings.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
