Histopathology of Enzootic Bovine Haematuria in the Darjeeling District of India

Abstract

SUMMARY Enzootic bovine haematuria of the Darjeeling district of India was identified histologically as “haematuria vesicalis bovis”, with the main lesions occurring in the urinary bladder. The lesion was one of carcinoma of the transitional epithelium. The transitional epithelium was grossly hyperplastic, and solid cords of transitional epithelium invaded and infiltrated into the submucosa producing transition-cell islets or nests, causing tissue reaction in the form of marked fibrosis, hyperplasia of lymph nodes, and proliferation of venules of the lamina propria to resemble haeman-giomatous conditions. Haemorrhage was observed to have occurred from these lesions via lenticular ulcers in the mucosa, and this gave rise to haematuria.