Abstract

ABSTRACT Purpose To report a histopathology and molecular biology study of an eyeball of a case of acute retinal necrosis (ARN). Methods Histopathology, immunohistochemistry and molecular biology of an enucleated globe of acute retinal necrosis 6 years after the onset of ARN. Results Histopathology showed persistence of chronic inflammatory cells with herpes virus inclusion body. Semi nested polymerase chain reaction showed varicella zoster virus. Conclusions Chronic inflammatory cells and viral genome can be persistent even after 6 years after the onset of ARN.

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