Abstract
The present study conducted on a fifty year old women affected with well differentiated papillary carcinoma, the histological changes of the thyroid left lobe was revealed, irregular shapes of thyroid follicles and degenerative alteration in the most follicles, Some thyroid follicles were enlarged and fill with colloid which contain on the large vacuoles, From another hand metaplastic changes was occur in the thyroid tissue of old women patient, So the epithelial linings of some thyroid follicles was projected as papillae which extended into the lumen of follicles, as well as the multifocal tumors of thyroid tissue was encapsculated by thick fibrous connective tissue, dilation and congestion of thyroid arteries and veins in parenchyma of thyroid left lobe.
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