HISTOPATHOLOGICAL STUDY OF NEOPLASTIC BREAST LESIONS IN A TERTIARY CARE CENTRE.

Abstract

We have studied 194 cases of neoplastic breast lesions over a period of 2 years (1 Jan 2020 to 31 December 2021) in MGM Medical college and Hospital, Aurangabad. The specimens were received in histopathology section of pathology department. Specimens were received in different forms such as Lumpectomy, trucut biopsy, simple mastectomy and MRM. Detailed gross examination of specimens (grossing of MRM: - according to AJCC protocol) followed by xation, thorough sampling and tissue processing. The different lesions were studied by histopathological examination and analysed. Neoplastic lesions were classied according to WHO classication (2017).Out of 194 cases, 75 cases had benign breast tumours and 119 had malignant tumours. Fibroadenoma (68 cases) was most common benign tumour followed by benign phyllodes (4cases), lactating adenoma (2 cases) and multiple ductal papilloma(1 case). Invasive carcinoma with no special type (104 cases) was most common malignant tumour. Special subtypes of invasive carcinoma found in our study were:- Invasive metaplastic carcinoma (1 case) Invasive lobular carcinomas (2cases), Invasive papillary carcinoma (1 case), Invasive mucinous adenocarcinoma (1 case), Solid papillary carcinoma (1 case), Invasive carcinoma with mucinous component (1 case) , Invasive carcinoma with neuroendocrine features (1 case) and Intracystic papillary carcinoma (2cases). Other malignant tumours included malignant phyllodes (2 cases) and malignant spindle cell neoplasm (3 cases). In our study, we found that malignant neoplasms were more common than benign neoplasms with Invasive breast carcinoma with no special type being the commonest malignant tumour. Histopathological study plays an important role in diagnosis of breast neoplasms and hence in treatment and prognosis.