HISTOPATHOLOGICAL STUDY OF ENDOMETRIALBIOPSIES IN ABNORMAL UTERINE BLEEDING

Abstract

Introduction: Excessive and painful bleeding from uterus is a common cause for distress among menstruating women, perimenopausal as well as post-menopausal. There are innumerable causes for abnormal bleeding from uterus. We carried out a retrospective study to enumerate the causes of abnormal uterine bleeding. Materials And Methods: Consecutive 200 slides of endometrial biopsies done for abnormal uterine bleeding were evaluated over a period of two years between June 2019 to May 2021. The slides were stained with haematoxylin and eosin stain. All the slides were evaluated, examined and reported by two experienced pathologists. The results were tabulated depending upon the age and diagnosis. Results: Commonest age group noted for abnormal uterine bleeding was between 41-50yrs. Disordered proliferative phase was the commonest (16%) functional cause of abnormal bleeding and diagnosis. The most common organic cause of abnormal bleeding was simple endometrial hyperplasia without atypia (28%). Endometrial carcinoma was diagnosed in 2 cases above 50yrs. Conclusion: Simple endometrial hyperplasiawas the most common cause of abnormal bleeding from uterus in our series. Atypical hyperplasia or endometrial carcinoma should be ruled out in post-menopausal age group.