Histopathological study of distribution of non-Neoplastic and neoplastic lesions in intestinal lesions

Abstract

Introduction: The small and large intestine account for the majority of GI tract. They are the sites of a broad array of diseases. These include both neoplastic and non-neoplastic, such as inflammatory lesions, polyps, cancerous growths. Colorectal cancer is the fourth ranking cancer worldwide, accounting for approximately 9% of all cancers. This study was conducted to study histopathological spectrum of lesions in intestine and their age and sex distribution. Materials and Methods: It was a retrospective study conducted in the Department of Pathology, GMERS Medical College and Civil Hospital, Sola, Ahmedabad from January 2018 to December 2018. The specimens included were endoscopic biopsies as well as resections of colon and part of intestine. Results: Total 131 intestinal specimens were received in our hospital over the period of January 2018 to December 2018. Overall non neoplastic lesions (87.8%) were more common than neoplastic lesions (12.2%). Most common non neoplastic lesion in small intestine was peptic ulcer and in large intestine was fistula. In large intestine, most common neoplastic lesion was adenocarcinoma. Conclusion: This study concludes that a variety of lesions occur in small and large intestine which have a vague presentation. Timely histopathological diagnosis and its clinical correlation help in early management and improve the survival. Keywords: Intestinal lesions, small intestine, large intestine, neoplastic, non-neoplastic, adenocarcinoma, malignant melanoma.