Histopathological spectrum of tumor and tumor like lesions of oral cavity and oropharynx in tertiary care hospital

Abstract

Background: Oropharyngeal cancers are most commonly observed cancers in Indian population. Oropharyngeal cancers have a poor prognosis. A histopathological study of lesions will give the exact cause and helps in initiation of optimal therapy at the earliest. Settings and design: Prospective study Aims: To study the histopathological changes in tumour and tumour like lesions of oral cavity and oropharynx Material and Methods: A prospective study was carried out in patients of oral cavity and oropharynx lesions. Total 100 biopsies and resected specimens were studied. Data included sociodemographic data, clinical features and histopathological diagnosis of the specimen. Statistical analysis used: Appropriate statistical tests Results and Conclusion: In our study we observed 10% tumor like lesions, 4% benign lesions, 4% premalignant lesions and 63% malignant lesions. Mucocele was the commonest tumor like lesion. Squamous cell carcinoma was the most common malignant lesion in our study seen in 95.2% cases. Out of 60 Squamous cell carcinoma cases, 11.6% had lymph node metastases and 3.3% showed lymphovascular invasion. In TNM staging of 14 cases who underwent resection with modified radical neck dissection, maximum number of cases belonged to Stage II (35.71%) and Stage IV (35.71%). Keywords: Histopathology, Oral cavity, Oropharynx, Tumor, Tumorlike.