Histopathological Spectrum of Thyroid Neoplasm - A Retrospective Study Done at Tertiary Cancer Care Hospital

Abstract

Thyroid lesions are fairly common & have a wide spectrum of diseases ranging from functional, immune mediated to neoplastic lesions. All thyroidectomy specimens were included in the study period of 1.5 years from September 2019 to February 2021 at our institute, a total of 10,200 biopsies were sent to our department for histopathological examination, out of which 7200 were diagnosed as malignant cases, of which 408 (5.6%) cases were thyroid cancer (TC) cases. One hundred forty-five (35.53%) out of 408 TC cases underwent thyroid surgeries, fifty consecutive cases who fulfilled the inclusion criteria were registered in our study. All grossed, processed, stained sections of haematoxylin and eosin were reviewed and observed under microscope. Average age of the patients suffering from TC was found 44.80 years. Female preponderance seen with F:M-1.38:1. Most common location of tumor was Right lobe of thyroid (32%) followed by Left Lobe (26%). Malignant lesions (96%) predominated over Benign lesions (4%). Papillary carcinoma thyroid was the most common malignancy (72%) followed by Follicular carcinoma (14%). Both benign cases were of Trabaecular Adenoma (4%). Majority of tumors were Unifocal (62%) followed by Mutlifocal (38%). Keywords: Thyroid Neoplasm, Benign and Malignant lesions