Abstract
Background: Psoriasiform dermatitis is a frequently encountered terminology in a wide variety of inflammatory dermatoses. It often poses challenges to both dermatologists and pathologists alike. Clinical features when considered alone may not be reliable, as they vary with both disease duration and treatment. On the contrary, histopathological material constitutes definite hard evidence, which can be preserved and will continue to be available for future review. The objective of the study is to study the histopathological findings in Psoriasiform dermatitis.Materials and Methods: This is a retrospective study in a tertiary care centre in Kerala, South India. All cases diagnosed as Psoriasis or mentioned as one of the differential diagnosis were included. The material included 66 skin biopsies. Patients with a previous diagnosis of the same were excluded from the study.Results: The lesions comprised 9% of the total number of skin biopsies. The age distribution pattern revealed that the highest percentage was in the 41-60 year age group (50%) with a male preponderance of 65%. Psoriasis was the most common lesion (60.60%) and Lichen simplex chronicus was the second most common lesion (10.60 %), encountered in the study.Conclusion: Some of the histopathological features are specific and characteristic for each entity like Psoriasis, Pityriasis rubra pilaris, Pityriasis rosea and Inflammatory linear verrucous epidermal nevus whereas some overlap in lesions like Prurigo nodularis, Lichen simplex chronicus and Allergic contact dermatitis. Hence, combination of proper clinical observation and histopathological study will give a conclusive diagnosis.
Highlights
Psoriasiform dermatitis (PD) encompasses a wide array of inflammatory dermatoses, some of which show both clinicalCorrespondence: It is an intimidating task even to experienced pathologists Age group(yrs) Psoriasis Lichen simplex chronicus (LSC)* Prurigo nodularis (PN) † < 20 2(5%) 5(12.5%) 2(29%) 24(60 %)
The present study is a comprehensive analysis of 66 cases of PD which constituted 9% of the 590 skin biopsies received at the centre over a period of one years
The most common features observed were hyperkeratosis, diffuse parakeratosis, uneven psoriasiform hyperplasia with supra papillary thickening and perivascular lymphocytic infiltrate in dermis. Five cases (7.57%) belonged to the category of Prurigo nodularis (PN)
Summary
Psoriasiform dermatitis (PD) encompasses a wide array of inflammatory dermatoses, some of which show both clinical. Correspondence: It is an intimidating task even to experienced pathologists Age group(yrs) Psoriasis LSC* PN † < 20 2(5%) 5(12.5%) 2(29%) 24(60 %). Psoriasiform dermatitis is a frequently encountered terminology in a wide variety of inflammatory dermatoses. It often poses challenges to both dermatologists and pathologists alike. Clinical features when considered alone may not be reliable, as they vary with both disease duration and treatment. Histopathological material constitutes definite hard evidence, which can be preserved and will continue to be available for future review. The objective of the study is to study the histopathological findings in Psoriasiform dermatitis
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