Histopathological spectrum of ovarian neoplasms - A 3 year hospital based study

Abstract

: Ovarian neoplasms are the fifth leading cause of cancer mortality among females worldwide. It is associated with poor survival due to late clinical presentation with most cases presenting at stage III or stage IV.: The present study was undertaken to assess the histopathological spectrum of ovarian neoplasms according to the World Health Organization classification (2020) and to determine the frequency and age distribution of these neoplasms in a tertiary care hospital. : This observational study was conducted over a period of 3 years (August 2016 to July 2019) in the Department of Pathology, Gandhi Medical College, Telangana, India. All ovarian neoplasm specimens were routinely processed and histopathological examination was done for each specimen.: A total of 115 cases were included in the study out of which 97 (84.34%) cases were benign, 6 (5.22%) cases were borderline and 12 (10.44%) cases were malignant. Surface epithelial tumours were the most common, followed by germ cell tumours and sex cord-stromal tumours. The age group of 31-40 years showed the largest percentage of ovarian neoplasms.: Ovaries are a common site for tumours. Most patients present at late stages due to non-specific symptoms. Ovarian neoplasms are associated with a variety of clinical and morphological features and hence a correct histopathological diagnosis is required to institute appropriate therapy.