Abstract

Introduction: Nephrectomy is a common procedure in urological practice done for various conditions like calculi, chronic pyelonephritis, malignancy, obstruction, injury, etc with wide range of morbidity and mortality. In our country there is increased in number of end stage renal disease treated with dialysis and transplantation. So it is mandatory to study the spectrum of renal disease with special emphasis on Chronic pyelonephritis. Methods: This study was carried out in the Department of Pathology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidhyapeeth University, Pondicherry. All the nephrectomy specimen received in the department over a period of three years (January, 2013 to December 2015) were included. A total of 34 cases of nephrectomy specimen were studied during this period. Results : Out of 34 cases of nephrectomy, 24 were done for inflammatory lesions, 8 cases for tumor and 2 cases shows cystic lesion. Out of 24 cases of pyelonephritis, 6 cases were associated with nephrolithiasis. Out of 8 tumor cases, 6 cases were Renal cell carcinoma. Conclusion: To conclude, Nephrectomies is mostly done for non-neoplastic lesion. CPN also seems to be associated with various findings like pyonephrosis, calculi, malignancies etc. Hence it is mandatory to study each CPN case in detail along with clinical and radiological findings. DOI:10.21276/APALM.1547

Highlights

  • Nephrectomy is a common procedure in urological practice done for various conditions like calculi, chronic pyelonephritis, malignancy, obstruction, injury, etc with wide range of morbidity and mortality

  • Simple nephrectomy is a common procedure in urological practice and it is indicated in patients with an irreversible damaged kidney resulting from symptomatic chronic infections, obstruction, calculus, severe traumatic injury and renal dysplasia[1].Kidney can be affected by various pathological conditions like cystic disease, glomerulonephritis, pyelonephritis, renovascular hypertension, obstruction, calculous disease, benign and malignant tumor, etc some of which may requires surgical treatment and some may requires medical treatment[2]

  • Chronic pyelonephritis with hydronephrosis is the most common type of nephrectomy specimen for non-neoplastic conditions due to increase in the incidence of pelviureteric junction obstruction by upper ureteric calculi, whereas in the neoplastic group, renal cell carcinoma is the most common due to increase in the incidence in chronic smokers[3]

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Summary

Introduction

Nephrectomy is a common procedure in urological practice done for various conditions like calculi, chronic pyelonephritis, malignancy, obstruction, injury, etc with wide range of morbidity and mortality. It is mandatory to study the spectrum of renal disease with special emphasis on Chronic pyelonephritis. Simple nephrectomy is a common procedure in urological practice and it is indicated in patients with an irreversible damaged kidney resulting from symptomatic chronic infections, obstruction, calculus, severe traumatic injury and renal dysplasia[1].Kidney can be affected by various pathological conditions like cystic disease, glomerulonephritis, pyelonephritis, renovascular hypertension, obstruction, calculous disease, benign and malignant tumor, etc some of which may requires surgical treatment and some may requires medical treatment[2]. It is mandatory to study the spectrum of renal disease with special emphasis on Chronic pyelonephritis.Radical or Partial nephrectomy is the treatment of choice for a greater proportion of patients with renal tumors[4]

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