Histopathological spectrum of neoplastic and non-neoplastic lesions of breast in a tertiary care centre in Bangalore

Abstract

Introduction: Breast lesions are a broad spectrum of lesions consisting of several distinct entities each with specific characteristics. Early evaluation of lesions with timely accurate diagnosis can alleviate anxiety of patients and also can be lifesaving. The most common cancer among Indian women is Breast cancer accounting to 25.8 per 100,000 women. Materials and Methods: A total of 100 cases of neoplastic and non-neoplastic lesions of breast were evaluated from June 2015 to June 2018 which were sent to department of pathology, Dr B R Ambedkar Medical College, Bangalore, Karnataka. Specimens were fixed in formalin of 10%. Appropriate areas were selected from the specimen and grossed, processed, sectioned, stained using haematoxylin and eosin and were observed under microscope. Results: out of 100 resected specimens, 19 cases were non-neoplastic, 46 were benign, and 35 cases were malignant. The most common benign breast lesion was Fibroadenoma (31%) and the most common malignant breast lesion was invasive carcinoma- No Special type (22%). Conclusion: Histopathological evaluation helps in distinguishing benign, insitu, borderline and malignant breast lesions and is the mainstay of accurate and confirmatory diagnosis. This helps in evaluating the risk of patient in developing cancer and appropriate treatment can be planned accordingly for each case. Keywords: Histopathology breast, Benign breast, Malignant breast lesions, Fibroadenoma, Invasive carcinoma.