Abstract
Introduction: Abnormal uterine bleeding (AUB) is the most common complaint in the gynecology out-patient department with different presentations and varied causes. Endometrial sampling is needed to investigate the cause of AUB. Aim: This study was done to evaluate histopathology of endometrium and observe the incidence of various endometrial pathology patterns in different age groups presenting with abnormal uterine bleeding. Materials and Methods: The current study was done at Malla Reddy Medical College for Women, Hyderabad, India, on cases of abnormal uterine bleeding who underwent endometrial sampling. A statistical analysis between age of presentation and specific endometrial causes was done using χ2 test. Results: We studied231 cases. The most common pattern observed was normal cycling endometrium (56.27%). The other morphological patterns were endometrial hyperplasia (19.48%), disordered proliferative pattern (5.62%), complications of pregnancy (4.76%), benign endometrial polyp (2.6%), chronic endometritis (2.16%) and carcinoma (0.86%). The most common age group presenting with AUB was 40-49 years (47.18 %) followed by 30-39years (33.76%). Endometrial causes of AUB and age distribution was statistically significant with P value<0.05. Conclusion: There is an age specific association of endometrial lesions. Atrophy and carcinoma endometrium are predominant in peri-menopausal and post-menopausal age. Endometrial curettings and biopsy proved to be an important diagnostic procedure for assessment and subsequent management of abnormal uterine bleeding.
Highlights
Abnormal uterine bleeding (AUB) is the most common complaint in the gynecology out-patient department with different presentations and varied causes
Type and duration of study: This was a retrospective observational study done on cases of abnormal uterine bleeding who underwent endometrial sampling from May 2015 to May 2017 in the Department of Pathology, Malla Reddy Medical College for Women in collaboration with the Department of Obstetrics & Gynaecology
Hyperplasia was observed in 45 patients (19.47%) of which 3 patients presented with atypical endometrial hyperplasia
Summary
Abnormal uterine bleeding (AUB) is the most common complaint in the gynecology out-patient department with different presentations and varied causes. Aim: This study was done to evaluate histopathology of endometrium and observe the incidence of various endometrial pathology patterns in different age groups presenting with abnormal uterine bleeding. Abnormal uterine bleeding (AUB) is a menstrual disorder affecting all age groups of women, at times reflecting serious underlying pathology [1]. It is defined as changes in frequency of menstruation, duration of flow, amount of blood loss or intermenstrual bleeding [2]. Endometrial sampling and subsequent histopathological study remain the gold standard for diagnosis of causes of AUB [4]. The endometrial histology shows different histopathological patterns in various causes of AUB
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