HISTOPATHOLOGICAL EVALUATION OF BONE TUMORS IN A TERTIARY CARE HOSPITAL IN GWALIOR, INDIA

Abstract

Background : Bone lesions are diagnostic challenges to surgical pathologists. Correlation of Histopathological study enables us to understand the spectrum of bone lesions and gives an idea of different bone tumors and tumor-like lesions in population among different age group and sex. To determine the spectrum of various bone tumors a Objective: nd their relative frequency at Gajraraja Medicsl College , Gwalior (M.P.). A retrospective review Materials and Methods: of histopathological reports of all bone specimens received in the Department of Pathology gajra raja medical college, gwalior for a period of 1years from August 2021- July 2022 was done. Results: Of the 55 histopathologically diagnosed bone lesions, male to female ratio was of 2.77:1. Age ranged from 6-83 years. Nonneoplastic lesions accounted for 38.18%, while neoplastic lesions accounted for 61.82%. Osteomyelitis was the most common and only nonneoplastic lesion encountered with 21cases (38.18%). Out of 34 cases of bone tumors, benign tumors made up to 67.65%, while the malignant tumor and tumor-like lesions made up 8.82% and 23.52%, respectively. Giant cell tumours with 10 cases (29.41%) and Ewing sarcoma with 3 cases (8.82%) were the most common benign and malignant tumors, respectively; while non ossifying fibroma with six cases (17.64%) was the most common tumor-like lesion. Femur was the most common site with 13(38.23%) occurrences followed by tibia with 6 (17.64%). Chronic osteomyelitis was Conclusion: the commonest nonneoplastic lesion. Among the bone tumors, giant cell tumour and Ewing sarcoma was the most common benign and malignant bone tumor, respectively