Abstract
Fibrolipoma is an unusual histologic variant of classical lipoma, in which neoplastic adipose cells are incorporated together with dense collagen, representing 1.6% of head and neck lipomas. The most common occurrence area of fibrolipoma is the buccal mucosa followed by the tongue. Histologically it is composed of mature adipose cells subdivided into lobes surrounded by dense connective tissue, which is what differentiates it from classic lipoma. It is reported a 68-year-old male, who presented a soft, oval, pediculated nodule with a smooth surface and painless located on the left upper lip mucosa measuring 0.9 x 0.6 cm with 4 months of evolution. Excisional biopsy was performed and the histopathological sections revealed neoplastic formation with presence of mature adipocytes and bundles of dense collagen, compatible with oral fibrolipoma without malignant characteristics. The case illustrates a rare entity of the oral cavity and the aspects with the literature are discussed.
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