Histopathological and Histochemical Studies on Lumbar Disc Lesion

Abstract

Histopathological and histochemical studies were performed on forty intervertebral discs which were taken by anterior discotomy and investigated the correlation between degenerative changes of discs and discogram.Staining methods were as follows, 1. H. E. 2. Azan Mallory 3. Alcian Blue 4. Metachromasia R 5. Ca S (von Kossa) 6. PAS R 7. Phosphorylase RResults1. The degenerative changes of the discs which were taken from disc lesion were higher than the degenerative process with aging.2. The degenerative order of the parts of the intervertebral disc is cartilagious plate, annular fiber and nucleus pulposus.3. The rate of coincidence between histopathological changes and discogram was 90%.