Abstract
Background &Objective:Chronic rhino sinusitis (CRS) is an inflammatory condition of the paranasal sinuses and the nasal passage lasting more than three months either with or without sinonasal polyps. This study aimed to report the common sinonasal lesions associated with CRS according to the histopathology results, to compare between clinical and histopathological diagnoses, and to compare between radiological and histopathological diagnoses of the sinonasal lesions.Methods:A retrospective study of the electronic records of 82 patients diagnosed with CRS with nasal polyps. All patients underwent endoscopic sinus surgery and histopathological examination of surgical biopsies. The collected data were analyzed using SPSS program. Coparison between clinical and histopathological diagnoses was done. This study was conducted at Alsafwa Consultative Medical center (ACMC) in Almukalla city, Hadhramout province in Republic of Yemen.Results:Out of 82 patients, the ages ranged from 4 to 90 years (mean: 34.48±17.74 years), and 54.88% were females. Inflammatory polyps were the most common lesion (31.4%), then allergic polyps (30.5%). Nasopharyngeal carcinoma (NPC) was reported in 9.8% of the lesions and all were unilateral. The results revealed strong compatibility between clinical and histopathological diagnoses (p<0.001, kappa= 0.215), and significant compatibility between radiological and histopathology diagnoses (p=0.007).Conclusion:Inflammatory and allergic polyps are the most common benign bilateral lesions associated with chronic rhinosinusitis, which can be correctly diagnosed clinically in most cases. Unilateral nasal polyps have high rates of malignancies and should be check carefully by endoscopy and histopathology. Computed tomography has some pitfalls in diagnosing of fungal sinusitis.
Highlights
Chronic rhino sinusitis (CRS) is an inflammatory condition of the paranasal sinuses and the nasal passage lasting more than three months with two or more of the following manifestations; nasal discharge, swelling nasal mucosa, pain and impaired smell.[1,2] It is a common disease that affects more than 10% of peoples in Europe.[3]Pak J Med Sci January - February 2020 Vol 36 No 2 www.pjms.org.pk 146CRS can be divided into two phenotypes, either inflammation associated with polyps (CRSwNP) or without polyps (CRSsNP).[1,2,4] In western countries, about 80% of CRS are CRS without nasal polyp (CRSsNP) and only 20% CRSwNP and eosinophilic inflammation (CRSwNP).[5]
Nasal polyps are tear-drop like growths that form in the nasal cavity or in the paranasal sinuses (PNS)
The results revealed strong compatibility between the clinical diagnoses and the histopathology results, (p
Summary
CRS can be divided into two phenotypes, either inflammation associated with polyps (CRSwNP) or without polyps (CRSsNP).[1,2,4] In western countries, about 80% of CRS are CRSsNP and only 20% CRSwNP.[5] Based on eosinophilic inflammation: CRSwNP can be subdivided into eosinophilic (Eos CRSwNP) and non-eosinophilic (Non-Eos CRSwNP).[4,6] Nasal polyps are tear-drop like growths that form in the nasal cavity or in the paranasal sinuses (PNS) They often accompanied allergies and chronic infections.[7]. Conclusion: Inflammatory and allergic polyps are the most common benign bilateral lesions associated with chronic rhinosinusitis, which can be correctly diagnosed clinically in most cases. Computed tomography has some pitfalls in diagnosing of fungal sinusitis
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