Abstract
Gastric cancer is a relatively common malignancy in Nigeria. Gastric cancer varies from region, being 4th to 20th in proportion to other malignancies. The symptom and signs are often non-specific with the early stages of the disease. This may be responsible for late presentation and poor prognosis. This is a 20-year retrospective analysis of 107 histopathologically confirmed gastric cancers in the department of pathology. This study aimed to analyze the Histopathological patterns of all the gastric cancer cases diagnosed in U.I.T.H Ilorin, over a twenty-year period. Gastric cancers were classified according to WHO 2010 and Lauren classification of gastric cancers. A total of 107 cases of gastric cancers diagnosed, that met the inclusion criteria, were analyzed with male: female ratio of 1.3:1 out of which epithelial malignancy accounted for 93.5% with tubular adenocarcinoma representing the commonest epithelial subtype. Epithelial malignancy is the commonest histological type in this area. Therefore, it is recommended that patients above 40 years with dyspepsia and other alarm features should undergo routine endoscopic screening.
Highlights
Gastric cancer is malignant neoplasm that arises in the stomach
Out of the total 516 gastric samples received over the period of study, 115 (22.3%) were histologically diagnosed as gastric cancers
During the same period of study, 3,806 cancer cases were histologically diagnosed at our centre out of which gastric cancers accounted for 3% with 115 cancer cases (Figure 1)
Summary
Gastric cancer is malignant neoplasm that arises in the stomach. It still remains a major health burden globally despite its declining incidence.[1] It is the fourth commonest cancer in the world with 985,600 new cases diagnosed annually and about 738,000 patients died yearly from the disease making it the second commonest cause of cancer related death.[2] Gastric cancers is a heterogeneous disease with various histopathological and epidemiological characteristics. Epithelial malignancy is the commonest histological type in about 95% of cases and there is interplay between the genetics and environmental factors in the pathogenesis of the. Histopathological Analysis of Gastric Cancers in University of Ilorin Teaching Hospital: A 20-Year Review.
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