Abstract
Intracanal medication in pulpectomy therapy is used between appointments with the objective of reducing pain and inflammatory processes in pulp and periapical tissues. Propolis has been known as a natural antibiotic and has been subject of medical and dental research due to its therapeutic properties such as antibiotic, analgesic and anti-inflammatory effects. ObjectiveThe aim was to carry out an in vivo evaluation of the periapical tissue response to propolis paste when used as an intracanal medication in the teeth of dogs after pulpectomy. Material and Methods72 dog's incisors were selected for the experiment. After biomechanical preparation the root canal was filled with a corticosteroid-antibiotic preparation, experimental propolis paste, non-medicament (negative control) or non-pulpectomy at all (positive control). The medications were left inside the root canal for 7, 14 or 28 days. At the end of the experimental period histological sections were prepared and all laboratories processes for Harris hematoxylin and eosin staining was proceeded followed by the analysis using an optical microscope. Sections were classified according to a score representing the inflammatory events observed: the presence of polymorphonuclear neutrophils, polymorphonuclear eosinophils, lymphocytes and plasma cells, macrophages and/or giant cells, fibrous condensation and abscesses. ResultsThere were statistically significant differences between the tissue reactions caused by the two substances being tested, after different experimental periods, with the periapical tissue that was in contact with propolis paste exhibiting fewer inflammatory reactions in comparison to corticosteroid-antibiotic preparation. ConclusionsThe low tissue responses from propolis paste suggest that this material could be considered as an option for root canal medication after pulpectomy.
Highlights
During endodontic treatment it may desirable or necessary to use an intracanal medication
In pulpectomy therapy intracanal medication is used between appointments with the objective of UHGXFLQJ SDLQ DQG LQÀDPPDWRU\ SURFHVVHV LQ SXOS and periapical tissues
During pulpectomy the pulp removal and chemical-mechanical preparation will lead the periapical tissues into an acute inflammatory process5,25, which explains the result of the vehicle group in this experiment
Summary
During endodontic treatment it may desirable or necessary to use an intracanal medication. In pulpectomy therapy intracanal medication is used between appointments with the objective of UHGXFLQJ SDLQ DQG LQÀDPPDWRU\ SURFHVVHV LQ SXOS and periapical tissues. The choice of this agent depends on its biologic characteristics: be nonirritant, control of the intensity and duration of. In spite of being originally designed as an otology medication, a commercial corticosteroidantibiotic preparation, Otosporin® is currently used in Dentistry as an intracanal medication due to its components: polymyxin B sulphate, neomycin sulphate, hydrocortisone and an aqueous base11,16 This preparation reduces vasodilation, decreases liquid exudation, and presents a direct vasoconstrictive action on small blood vessels. Though this combination has many properties that are desirable as a pulpectomy intracanal medication, if it is used for prolonged periods it can reduce cellular metabolic activity and even impede or delay tissue repair
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
