HISTOPATHOLOGIC STUDIES ON THE SALIVARY GLANDS OF RABIC DOGS

Abstract

Since June, 1950 we have extracted and examined parotid and madibular glands from 15 cases of rabic clogs which occurred in Gurnma-ken, with the following results : (1) On parotid glands no remarkable degeneration or inflammatory changes were observed. There was generally noted atrophy.(2) On mandibular glands were observed interstitial inflammation with strong degeneration of eipthelium.(3) Interestitial inflammation developed diffusely or in scattered focuses and consisted in cell infiltration chiefly of lymphocytes, plasma cells and of some histiocytes. This reaction form is same as was observed on inflammatory focuses in the tissue of other organs of rabic dogs.(4) As for degenerative focuses were noted pictures of various stages ranging from vacuole and karyorrhexis to destruction of cellbodies.(5) The relation between the degeneration and interstitial inflammation of the mandibular glands cannot be said the sequence of the latter to the former as was reported by Orth, Gruber et al. We would rather regard it the interstitial inflammation accompanied by degeneration.(6) Negri's bodies could not be demonstrated.(7) We could not explain the cause of the remarkable difference in pathologic changes between the parotid and mandibular glands.