Abstract
After treatment of purified chromatin with dimethyl adipimidate (a reversible crosslinking reagent) a number of histone oligomers could be isolated in the soluble form from the chromatin. It was shown that all five histones take part in the dimethyl adipimidate-induced oligomer formation. Only a few kinds of histone oligomers (with unknown composition) could be isolated in the soluble form after treatment of chromatic with formaldehyde.
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