Abstract
Background: Prostatism is one of the commonest health concerns in geriatric population with significant morbidity and mortality. The incidence of it increases with age. Histopathological evaluation plays a major role in the diagnosis and management of Prostate lesions. Aims and Objectives: To study the spectrum of prostate specimens encountered by the pathologists and to categorize them based on their histomorphological features and to correlate it with the clinical and other laboratory parameters. Material and methods: Hematoxylin and Eosin sections of 100 prostatic biopsies received in the department of Pathology of a tertiary care centre over a period of 18 months were studied. Relevant clinical and laboratory data were collected. Results: Out of 100 prostatic biopsies studied, 91 were TURP and 9 were core biopsies. Prostatic lesions was common in the age group of 61-70 years. 75% of cases were benign with or without prostatitis, 15% malignant and 10% cases were pre malignant. 25% cases were found to have associated prostatitis with the benign and malignant lesions. The most common microscopic feature in benign cases was fibromuscular hyperplasia. Conclusion: The present study shows that benign lesions are more common than the malignant ones. Among benign lesions, BPH was the most common entity. The most common age group affected was 7th decade.
Highlights
The incidence of prostatism increases with age beyond 6th decade and is one of the commonest health concerns in geriatric population with significant morbidity and mortality
Histopathological evaluation plays a major role in the diagnosis and management of Prostate lesions as both benign and malignant prostatic lesions present with similar clinical presentation
Prostatic specimens have become a significant workload for a pathologist and Trans Urethral Resection Prostate (TURP) specimens and Prostatic biopsies often pose a diagnostic challenge for the practicing pathologists
Summary
The incidence of prostatism increases with age beyond 6th decade and is one of the commonest health concerns in geriatric population with significant morbidity and mortality. We aimed to study the spectrum of prostatic specimens received in a tertiary care hospital and categorize the histomorphological features. Prostatism is one of the commonest health concerns in geriatric population with significant morbidity and mortality. The incidence of it increases with age. Histopathological evaluation plays a major role in the diagnosis and management of Prostate lesions. Aims and Objectives: To study the spectrum of prostate specimens encountered by the pathologists and to categorize them based on their histomorphological features and to correlate it with the clinical and other laboratory parameters.
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