Histomorphological study of salivary gland lesions: A study in tertiary care centre, Bangalore

Abstract

Introduction: Salivary gland lesions are morphologically and clinically diverse group of lesions which is difficult task for histomorphological interpretation. Since salivary gland tumours are uncommon owing to limited experience with them. The salivary gland system comprises three pairs of major glands (parotid, submandibular and sublingual) and about 500-1000 lobules of minor glands dispersed in the submucosa of the oral cavity. Neoplastic and non-neoplastic lesions arises from major and minor salivary glands. Materials and Methods: Present study was done for 3 years from June 2015 to June 2018. The study was done on 50 specimens from patients with salivary gland lesions which are referred to the department of pathology, DR. B R Ambedkar medical college, Bangalore, Karnataka. The gross examination was done after fixing specimen in 10% formalin and sections were stained with haematoxylin and eosin. Results: Out of 50 cases, 35 cases are neoplastic, and 15 cases are non-neoplastic. Among 35 neoplastic lesions, 20 cases are benign, and 15 cases are malignant. Most common benign tumour of salivary gland is pleomorphic adenoma followed by Warthin’s tumour. Most common malignant tumour of salivary gland is mucoepidermoid carcinoma followed by adenoid cystic carcinoma. Most common non-neoplastic lesion is chronic sialadenitis. Conclusion: From the present study, it is evident that histomorphological examination is the mainstay for the diagnosis and categorization of neoplastic and non-neoplastic lesions of salivary gland. Keywords: Salivary gland, Pleomorphic adenoma and Mucoepidermoid carcinoma.