Histomorphological Pattern of Splenectomy Specimens: A FiveYear Study in a Tertiary Teaching Hospital

Abstract

Spleen, being the largest organ of the mononuclear phagocytic system is involved in many systemic inflammations, generalized haematopoietic disorders as well as metabolic disorders.By its anatomic location where it is not protected by a bony cage,makes it prone to traumatic injury.Splenectomy is also one of the modalities of treatment in haematological disorders like thalassaemias which will help in minimizing the need, frequency and complications of repeated blood transfusions.On the other hand,post-splenectomy complications may be life-threatening with a mortality of 50% to 80%. Nowadays, attempts are made to save splenic functions by performing repair of laceration in injuries or by partial splenectomy. Fine needle aspiration cytology(FNAC) ,a non-invasive diagnostic procedure may be helpful in some conditions without undergoing the invasive surgical approach. Splenic pathology has not been much studied in this region.The retrospective study was taken up to highlight the histomorphological pattern of surgically removed splenectomy specimens and to correlate with with the clinical conditions.A total of 20 splenectomy specimens were received in the five-year period and the findings are highlighted.