Abstract

Introduction: The incidence of skin cancer is increasing exponentially around the world. This study aims to analyze different malignant skin tumors concerning age pattern, gender, and site-wise distribution.
 Materials and Methods: This is a descriptive cross-sectional hospital-based study carried out in the Department of Pathology, a tertiary care center for over ten years from April 2011 to March 2021. All malignant skin tumors arising from the epidermis along with melanocytic and adnexal tumors were included in the study.
 Results: A total of 208 cases of skin malignancies among which 117 (56.3%) cases were males and 91 (43.8%) females with a male to female ratio of 1.3:1. Overall, the majority were seen in the sixth decade 49 (23.6%) with head and neck region 113 (54.3%) being the commonest site of involvement. Basal cell carcinoma 79 (38%) was the most frequent non-melanoma skin cancer followed by squamous cell carcinoma 75 (36.1%). A maximum number of basal cell carcinoma were observed in the sixth decade 19 (24.1%) whereas squamous cell carcinoma in the seventh decade 21 (28%) cases. Other skin cancers were malignant melanoma 31 (14.9%), verrucous carcinoma 13 (6.3%), trichilemmal carcinoma five (2.4%), sebaceous carcinoma two (1%), and one case each of eccrine carcinoma, malignant nodular hidradenoma, and malignant proliferating trichilemmal tumor.
 Conclusions: Skin malignancies were seen in the sixth decade with male preponderance. Overall, the head and neck region was the commonest site of involvement. Basal cell carcinoma was the most frequent non-melanoma skin cancer followed by squamous cell carcinoma.

Highlights

  • The incidence of skin cancer is increasing exponentially around the world

  • Skin malignancies were seen in the sixth decade with male preponderance

  • Basal cell carcinoma was the most frequent non-melanoma skin cancer followed by squamous cell carcinoma

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Summary

Introduction

The incidence of skin cancer is increasing exponentially around the world. This study aims to analyze different malignant skin tumors concerning age pattern, gender, and site-wise distribution. Skin is the largest and heterogeneous organ of the body with varied elements of ectodermal and mesodermal origin, capable of producing various types of skin tumors.[1,2] The incidence of skin cancer is increasing exponentially around the world.[3] Three most frequent primary skin cancers are basal cell carcinoma (BCC), squamous cell carcinoma (SCC), in combination referred to as non-melanoma skin cancers (NMSC), and malignant melanoma (MM).[4]. The number of new cases of NMSC was found to be almost 3.7 times higher than MM.[5] The incidence of skin tumors varies widely in different parts of the world.

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