Abstract
still born fetuses of age group (13-40weeks) were studied macroscopically and microscopically to observe the sequential changes in the obliteration process of Ductus arteriosus. The Ductus arteriosus (DA) was found to originate either from left pulmonary artery or from the bifurcation of pulmonary trunk. Significant changes in the length, outer and inner diameter of DA were observed in different gestational period. The tunics of DA showed structural changes in arrangement of muscle layers, appearance of intimal cushion, organization of elastic and collagen fibers. The proliferation and migration of muscle fibers from tunic media and formation of intimal cushion marked the process of gradual closure of DA.
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