Histological study on the beneficial effect of Spirulina for aorta from damage induced by D-galactose

Abstract

Spirulinal powder supplementation is being studied to see if it can help slow the progression of aging in the heart. As a control group, twenty male rabbits were randomly and equally divided into four groups, each receiving 150 mg/kg BW of d-galactose S/C daily as Group II; 500 mg/kg BW of Spirulinal orally as Group III; and 150 mg/kg BW daily S/C administration of d-galactose with 500 mg/kg BW orally as Group IV for four weeks. Using the specific stain Masson's Trichrome, stained sections of the aorta from the D-gal group (GII) and the combination group (CII) exhibit histological changes in the tissue (GIV). Tissue slices stained with Masson's Trichrome stain reveal the location of collagen and muscle fiber accumulation, which appears as a red keratin and muscle fiber accumulation area. Our findings show that Spirulinal powder, a feed supplement, has a protective effect against heart aging.