Abstract

The use of medicinal plants has attained a commanding role in health system all over the world. This involves the use of medicinal plants not only for the treatment of diseases but also as potential material for maintaining good health and conditions. Many countries in the world, that is, two-third of the world’s population depends on herbal medicine for primary health care. Homalium letestui is an evergreen tree. The plant has been of immense benefit to traditional users. A bark-decoction, combined with other medicinal plants, is taken by draught for orchitis, and bark-scrapings enter a prescription given to a newly delivered woman. In this study the histological effect of the ethanol stem extract of Homalium lestetui on rat paracetamol induce liver injury was carried out using H&E and Gordon and Sweet silver impregnation Technique.

Highlights

  • The liver is a reddish brown organ with four lobes of unequal size and shape [1]

  • Histological work suggests that the plant may prevent or protect the liver architecture

  • It is connected to two large blood vessels, one called the hepatic artery and one called the portal vein

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Summary

Introduction

Human liver normally weighs 1.44–1.66 kg, and is a soft, pinkish-brown, triangular organ. It is both the largest internal organ (the skin being the largest organ overall) and the largest gland in the human body. It is located in the right upper quadrant of the abdominal cavity, resting just below the diaphragm. The hepatic artery carries blood from the aorta, whereas the portal vein carries blood containing digested nutrients from the entire gastrointestinal tract and from the spleen and pancreas

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