Abstract
Aim & Objectives: To correlate the Histological adaptive changes in adrenal gland in response to chronic stress since it is a stress responding organ common to both the HPA axis & Sympathoadrenomedullary axis . Material & Methods: Duration of study – Two yrs Place of study: Dept. of Anatomy, FMT, Pathology of MKCG MC , Berhampur & SCB MC, Cuttack . Material for study – Right and Left adrenal . No. of Suicidal cases -Hundred No. of Accidental cases (control)-Twenty . Results: On Histological study it was found that the cells in Zona Glomerulosa showed increased nuclear density. Hypertrophy and hyperplasia of Zona Fasciculata with intracytoplasmic lipid depletion varying from mild to extensive giving rise to parenchymal cord-like arrangement of cells .Sinusoidal prominence in all the three zones including medulla.A normal pattern of Adrenal gland is informative of receipt of sudden violence i.e accident. Conclusion: The present study concludes and supports the idea that chronic stress as in suicide usually induces adrenal growth which may have implications for forensic people in revealing the cause of unknown deaths.
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