Abstract
The study is a retrospective cross-sectional study carried out in the Department of Pathology of Premier Hospital, Abuja, on specimens received over a one-year period. Four hundred and eighty-six samples of endometrial biopsies and curettings from women presenting with abnormal uterine bleeding sent to the histopathology laboratory were analyzed. The most common biopsies were those of product of conception which accounted for 304 cases (62.6%). Most of the cases of endometrial hyperplasia were typical. Endometritis and chorioamnionitis were the inflammatory conditions seen. Twenty-three women had molar pregnancies. The most common cause of abnormal uterine bleeding in this population is retained products of conception. There may be need to retrain some of the staff involved in the management of pregnancy related complications. There is need to further evaluate pregnancy related complications to ascertain the causes and circumstances responsible for them so as to appropriately direct interventional protocols.
Highlights
Endometrial biopsies are obtained for a number of reasons that include abnormal uterine bleeding in certain age groups, incomplete abortions, or suspected neoplasia and the endometrium may be sampled prior to certain procedures to treat infertility to determine the phase of the cycle to guide further tests or treatments [1]
The protocol to handle any endometrial sampling material is guided by the clinical indication for the specimen submission which may be for evaluation of infertility or preparation for In Vitro Fertilization (IVF), evaluation of abnormal uterine bleeding, and follow-up of a previous cytological or histological diagnosis [2]
The endometrium may be examined as part of a hysterectomy specimen and may be the site of a primary or secondary neoplastic process
Summary
Endometrial biopsies are obtained for a number of reasons that include abnormal uterine bleeding in certain age groups, incomplete abortions, or suspected neoplasia and the endometrium may be sampled prior to certain procedures to treat infertility to determine the phase of the cycle to guide further tests or treatments [1].The protocol to handle any endometrial sampling material is guided by the clinical indication for the specimen submission which may be for evaluation of infertility or preparation for In Vitro Fertilization (IVF), evaluation of abnormal uterine bleeding, and follow-up of a previous cytological or histological diagnosis [2].The endometrium may be examined as part of a hysterectomy specimen and may be the site of a primary or secondary neoplastic process.Cases of DUB may have structural or functional causes depending greatly on the age of the patient and clinical history [1].Some studies showed infertility as the most common indication for endometrial biopsy and secretory phase endometrium as the commonest morphologic pattern encountered [3].A low prevalence of tuberculous endometritis and endometrial carcinoma was noted in similar studies [3]. Endometrial biopsies are obtained for a number of reasons that include abnormal uterine bleeding in certain age groups, incomplete abortions, or suspected neoplasia and the endometrium may be sampled prior to certain procedures to treat infertility to determine the phase of the cycle to guide further tests or treatments [1]. The protocol to handle any endometrial sampling material is guided by the clinical indication for the specimen submission which may be for evaluation of infertility or preparation for In Vitro Fertilization (IVF), evaluation of abnormal uterine bleeding, and follow-up of a previous cytological or histological diagnosis [2]. Some studies showed infertility as the most common indication for endometrial biopsy and secretory phase endometrium as the commonest morphologic pattern encountered [3]. A low prevalence of tuberculous endometritis and endometrial carcinoma was noted in similar studies [3]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
