Histological justification of the application of materials based on biomodified hyaluronic acid in combination with xenogenic osteoplastic material for maxillary alveolar bone augmentation before dental implantation

Abstract

The objective of the present study was the comparative evaluation of the effectiveness of using the composition of xenogenic osteoplastic material and materials based on biomodified hyaluronic acid for maxillary alveolar bone augmentation before dental implantation based on the results of histological investigations. The material for the study was bone tissue biopsies obtained with the use of a trephine at the stage of installation of the dental implants. The 4 micron sections prepared with a microtome were examined under different modes of light microscopy: bright field, dark field, phase contrast and polarization. The results of the study gave evidence of the formation of the endogenous bone tissue instead of the osteoplastic material in both the experimental and the control groups of the patients. Using of the xenogenic osteoplastic material in combination with preparations of biomodified hyaluronic acid gave the best results during sinus lift operation, since in these cases the bone of the most mature structure was formed, and in most cases there were no fragments of the implanted osteoplastic material. Nevertheless, the quality of the bone regenerate made it possible to install dental implants 6 months after the sinus lift in all groups.