Histological examination of rabbit tissues and internal organs during experimental infection with Trichinella spiralis larvae

Abstract

The purpose of the research is to conduct a histological examination of the tissues and organs of rabbits experimentally infected with Trichinella spiralis larvae.Materials and methods. Necropsy was performed and organ and tissue samples were taken for histological studies 45 days after the experimental infection of White Giant rabbits with T. spiralis. The samples were fixed in 10% buffered formalin. Histological preparations: paraffin sections 4 μm thick, stained with hematoxylin and eosin.Results and discussion. A complete histological examination of the dermis, muscles and internal organs in experimental trichinellosis was conducted. The effect of T. spiralis larvae on the body of rabbits and the pathological changes in organs and tissues were determined. Pathological changes of an inflammatory nature were established in the heart muscle, kidneys, lungs, small intestine, spleen and muscle tissue and the muscle layer of dermis with the presence of accumulation of lymphocytes and eosinophils. Colored illustrations of the obtained sections with a detailed description are provided.