Abstract
The use of detergents has become widespread and is growing. The increase in population and use of detergent threatens the life of organisms in the ecosystem. In this study, the histological effects of linear alkyl benzene sulphonic acid on primordial germ cell (PGC) migration and gonad formation in zebrafish were investigated after application of 0.25 0.5 and 1 mg/L of linear alkyl benzene sulphonic acid to embryos. Samples of embryos and larvae were collected for 60 days and the effects of linear alkyl benzene sulphonic acid on PGC migration and gonad development were examined by histological procedures. The localization and migration pathway of PGCs and structures of the gonads were inspected by Periodic Acid Schiff (PAS), alkaline phosphatase, toluidine blue and Best?s carmine staining. Primordial germ cells were observed in ectopic regions and delayed gonadal development and histopathological changes in gonad structures were observed. We concluded that linear alkyl benzene sulfonic acid exposure has a negative effect on the reproduction system of zebrafish.
Highlights
Detergents are effective cleaning products in the form of powders, granules, gels or liquids that contain one or more anionic surfactants
We investigated the effects of LAS on primordial germ cell (PGC) and gonad formation in zebrafish
Primordial germ cells were determined from the first day post fertilization and migration routes were observed in both control and exposure groups
Summary
Detergents are effective cleaning products in the form of powders, granules, gels or liquids that contain one or more anionic surfactants. They are common contaminants in aquatic ecosystems, and pollution caused by detergents has increased significantly. As detergent waste contains phosphate, it produces toxic effects in aquatic organisms and causes eutrophication in aquatic ecosystems. Detergents have dermatological, teratogenic and biochemical effects, and produce histological damage in fish, mice, pigs and humans [2,3,4,5,6,7,8,9,10,11,12]
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