HISTOLOGICAL CHANGES IN PIGLETS WITH THE ASSOCIATIVE COURSE OF SALMONELLOSIS AND EIMERIOSIS

Abstract

The article describes the microscopic changes found during the autopsy of piglets that died from the associative course of salmonellosis and eimeriosis. In case of the associative course of salmonellosis and eimeriosis, clinical forms of the disease are recorded: severe intestinal exicosis, an infectious-toxic form with a severe and very severe course and a severe toxic-dystrophic form. At the histological level, with a mixed course of salmonellosis and eimeriosis, typical changes in the small intestine were found in all cases: congestive hyperemia, edema, hemorrhages, fibrin, granular dystrophy and villous necrosis, granular dystrophy and necrosis of the glandular epithelium, proliferation; in the large intestine: congestive hyperemia and edema, hemorrhages, granular degeneration and necrosis of the crypt epithelium, fibrin, proliferation; in the liver: congestive hyperemia, edema, hemorrhages, granular and fatty degeneration of hepatocytes, dry milliary areactive necrosis, proliferation around the triads, granulomas in the parenchyma; in the kidney: intracapillary glomerulonephritis; granular dystrophy of the tubular epithelium, rhexis and pycnosis of the tubular epithelial nuclei, proliferation and hyperemia in the interstitium; in the heart: congestive hyperemia, hemorrhages, edema, granular dystrophy of myocardial fibers, milliary areactive dry necroses, Zenker’ necrosis, proliferation; in the lungs: congestive hyperemia, catarrhal bronchopneumonia, proliferation in the interstitium, alveolar emphysema; in the spleen: congestive hyperemia, edema, hemorrhage, follicular necrosis; in the mesenteric lymph nodes: congestive hyperemia, edema, hemorrhage, follicular hyperplasia; in the brain: congestive hyperemia, edema.