Histological changes and diagnostic value of immunoglobulin G/M to Helicobacter pylori in gastric cancer patients

Abstract

Stomach cancer is believed to be one of the most common cancers that lead to death. In Iraq, stomach cancer occupies the seventh place of cancer occurrence in both sexes and is counted as one of the ten most common cancers. The current study is designed to explore the link between Helicobacter pylori (H.pylori) infection and the development of incidences of stomach cancer. In addition, related age and gender were also studied. Histological examinations of stomach biopsies were performed in suspected people to evaluate stomach cancer occurrences. Of the 40 patients with stomach cancer, the infection of H. pylori was emphasized in 34 (66.66%) with serum IgG/IgM, which reflected a significant frequency for infection of H. pylori in stomach cancer patients. The study also showed that males with H. pylori infection record a higher percentage than female patients with stomach cancer. Moreover, the results revealed that age is also connected to H. pylori infection. Based on the above findings, monitoring infected people with H. pylori might be an excellent strategy to control stomach cancer occurrences. Keywords: Stomach cancer, Infectious diseases, IgG, IgM, H. pylori.