Abstract
1. This paper is a preliminary report on the eosinophilic vesicles found in the head epidermis of Blepsias cirrhosus.2. Such vesicles occurred also in the following three species: Cottus nozawae, Hemitripterus villosus and Myoxocephalus sp. Accordingly, the vesicles seemed to be not a morbid structure, but a wide-spread one among the fishes belonging to the family Cottidae.3. They were roundish oval or pear shaped, and of variable sizes, and their tips occasionally opened to external. They were generally prominent in the species supplied with few mucous cells.4. The contents of the vesicles looked light yellow or colorless, and were stained more easily with acid dyes, especially with eosin, than with the basic ones. They exhibited considerable variations in staining intensity and color tone according to whether they consisted of gross granules or fine ones.5. The chemistry and the function of these vesicles need further investigation.
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