Abstract
Introduction: Brunner’s glands, located in the submucosa of the proximal duodenum, in general produce a mucous secretion and exist in all mammalian species. Aims and objectives: The main purpose of present work is to histologically observe the brunner’s glands of guinea pig and study different types of mucin secreted by them using various histochemical staining techniques. Materials and Methods: Tissues were taken from the proximal part of duodenum of 10 guinea pigs and then subjected to various histochemical stains like AB at both pH 1 and 2.5, PAS, Diastase digestion, PAS- Phenyl hydrazine, AB pH 2.5- PAS and AB pH2.5- Saffranin. Result: The Brunner’s glands of guinea pig were composed of only mucous acini densely packed within the submucosa. The secretion produced is a mixture of both acid and neutral mucins. Conclusion: Mucins have been classified into neutral and acidic types, the latter being subdivided into sulphomucins and sialomucins. In guinea pig the secreted acid mucin contain mixture of both sialomucin and
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
