Abstract
The classification of salivary gland neoplasms is dynamic and continues to evolve, as reflected in the World Health Organization (WHO) Classification of Head and Neck Tumours. This includes recently identified and defined tumor types, such as intraductal carcinoma and cribriform adenocarcinoma of minor salivary glands. It also includes new nomenclature for well-established tumors, most notably, polymorphous adenocarcinoma (PAd) for polymorphous low-grade adenocarcinoma (PLGA) and secretory carcinoma (SC) for mammary analogue secretory carcinoma (MASC). The WHO classification separates neoplastic entities primarily on tumor morphology and predicts biologic behavior. Newly identified and continually growing numbers of specific molecular alterations in salivary gland tumors have buttressed the morphologic-based classification.
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