Abstract
Objective: To investigate the relationship among the latest WHO classification of thymoma, myasthenia gravis (MG) and clinical stages. Methods: To review the pathological sections of 74 patients with thymoma from 1980-2004 using WHO classification (1999), the statistical software was used to analyze the relationship among the WHO classification, MG and clinical stages. Results: (1) Two cases of type A, 23 cases of type AB, 4 cases of type B1, 27 cases of type B2, 16 cases of type B3 and 2 cases of type C were classified. Type B2 more likely accompanied MG (P<0.05), while none with MG occurred for type C. (2) One patient was in stage I, 30 were in stage II, 38 were in stage III, and 5 were in stage IV. The latest histologic classification was significantly correlated with Masaoka stages (P<0.01). Conclusion: The latest WHO classification was correlated with occurrence of MG and finely reflected clinical stage. It can also evaluate the prognosis of patients.
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