Abstract

Chick embryos were given a teratogenic dose of Malathion at the 5-day incubation stage and the effects of this treatment on the histogenesis and histochemistry of the yolk sac were studied. The Malathion caused a decrease in the amount of hemopoietic tissue. Also, the endodermal cells had decreased glycogen and lipid storage, decreased glycoprotein and acid mucopolysaccharide staining intensities, and decreased acid phosphatase activity. These observations suggest an interference with carbohydrate and lipid uptake and storage by the yolk sac.

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