Abstract
The study designed to investigate the histological modification of heart tube during the development stage in local domestic rabbits embryo. The experimental animals were distributed into four groups each group consist of one male Rabbit and three female Rabbits. The pregnant female in all groups were sacrificed at the end of each period. The result showed the early stage of heart development at (4, 6, 8 and 10) days of gestation period, the first embryonic evidence of embryo was the neural tube formation belong the longitudinal axes of embryo. The result noted the primary divisions of neural tube in cephalic region of embryo. The result noted at six day of development time showed prominent cardiogenic plate located in limited region called intra embryonic cavity. The micrograph at eight day of heart development showed the heart tube have prominent wide ends, while at ten day noted establishment of primitive heart regions which included the truncus areriosus, bulbo cordis, atrium, ventricle and sinus venosus .
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